BDBM18366 (2R,3R,5S,6R)-2,6-bis(hydroxymethyl)piperidine-3,4,5-triol::alpha-homonojirimycin (alpha-HNJ)
SMILES: OC[C@H]1N[C@H](CO)[C@H](O)C(O)[C@@H]1O
InChI Key: InChIKey=CLVUFWXGNIFGNC-QTSLKERKSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
alpha-Glucosidase (alpha-Glu) (Homo sapiens (Human)) | BDBM18366 ((2R,3R,5S,6R)-2,6-bis(hydroxymethyl)piperidine-3,4...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 4.5 | 37 |
Hokuriku University | Assay Description Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4... | Bioorg Med Chem 14: 7736-44 (2006) Article DOI: 10.1016/j.bmc.2006.08.003 BindingDB Entry DOI: 10.7270/Q2BZ649B | |||||||||||
More data for this Ligand-Target Pair |