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SMILES: COc1cccc(OC)c1-c1cc(F)cc(c1)C(CC(O)=O)c1ncco1

InChI Key: InChIKey=KPAYSTKBZUTPAB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 183845   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysosomal protective protein [29-480]


(Homo sapiens (Human))		BDBM183845
PNG
(US9150526, 98)
Show SMILES COc1cccc(OC)c1-c1cc(F)cc(c1)C(CC(O)=O)c1ncco1
Show InChI InChI=1S/C20H18FNO5/c1-25-16-4-3-5-17(26-2)19(16)13-8-12(9-14(21)10-13)15(11-18(23)24)20-22-6-7-27-20/h3-10,15H,11H2,1-2H3,(H,23,24)
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Similars
US Patent
n/an/a 18n/an/an/an/a6.037



Sanofi

US Patent


Assay Description
Recombinant human cathepsin A (residues 29-480, with a C-terminal 10-His tag; R&D Systems, #1049-SE) was proteolytically activated with recombinant h...

US Patent US9150526 (2015)


BindingDB Entry DOI: 10.7270/Q2QR4VXP
More data for this
Ligand-Target Pair