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SMILES: COc1cccc(OC)c1-c1cc(cc(c1)C(F)(F)F)C(CC(O)=O)c1nnc(C)o1

InChI Key: InChIKey=UOBWXOMMEIGGEB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 183942   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysosomal protective protein [29-480]


(Homo sapiens (Human))		BDBM183942
PNG
(US9150526, 205)
Show SMILES COc1cccc(OC)c1-c1cc(cc(c1)C(F)(F)F)C(CC(O)=O)c1nnc(C)o1
Show InChI InChI=1S/C21H19F3N2O5/c1-11-25-26-20(31-11)15(10-18(27)28)12-7-13(9-14(8-12)21(22,23)24)19-16(29-2)5-4-6-17(19)30-3/h4-9,15H,10H2,1-3H3,(H,27,28)
PDB
MMDB

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PC sid
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Similars
US Patent
n/an/a 2n/an/an/an/a6.037



Sanofi

US Patent


Assay Description
Recombinant human cathepsin A (residues 29-480, with a C-terminal 10-His tag; R&D Systems, #1049-SE) was proteolytically activated with recombinant h...

US Patent US9150526 (2015)


BindingDB Entry DOI: 10.7270/Q2QR4VXP
More data for this
Ligand-Target Pair