BDBM184210 US9150577, 67

SMILES: CC(C)n1c(NC(=O)c2ccc3cc4C(=O)N[C@H](C)[C@H](C)n4c3c2)nc2ccccc12

InChI Key: InChIKey=CYXJILQKECKNGH-CABCVRRESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha 2 (Homo sapiens (Human))	BDBM184210 (US9150577, 67) Show SMILES CC(C)n1c(NC(=O)c2ccc3cc4C(=O)N[C@H](C)[C@H](C)n4c3c2)nc2ccccc12 |r| Show InChI InChI=1S/C24H25N5O2/c1-13(2)28-19-8-6-5-7-18(19)26-24(28)27-22(30)17-10-9-16-11-21-23(31)25-14(3)15(4)29(21)20(16)12-17/h5-15H,1-4H3,(H,25,31)(H,26,27,30)/t14-,15+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...				US Patent US9150577 (2015) BindingDB Entry DOI: 10.7270/Q2GB22V6
					More data for this Ligand-Target Pair