BDBM184232 US9150577, 92

SMILES: C[C@H]1CNC(=O)c2cc3ccc(cc3n2[C@H]1C)C(=O)Nc1nc2ccccc2n1CCCN(C)C

InChI Key: InChIKey=SEPYENAOZGWPCC-ROUUACIJSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha 2 (Homo sapiens (Human))	BDBM184232 (US9150577, 92) Show SMILES C[C@H]1CNC(=O)c2cc3ccc(cc3n2[C@H]1C)C(=O)Nc1nc2ccccc2n1CCCN(C)C |r| Show InChI InChI=1S/C27H32N6O2/c1-17-16-28-26(35)24-14-19-10-11-20(15-23(19)33(24)18(17)2)25(34)30-27-29-21-8-5-6-9-22(21)32(27)13-7-12-31(3)4/h5-6,8-11,14-15,17-18H,7,12-13,16H2,1-4H3,(H,28,35)(H,29,30,34)/t17-,18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...				US Patent US9150577 (2015) BindingDB Entry DOI: 10.7270/Q2GB22V6
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