BDBM184295 US9150577, 171

SMILES: C[C@@H]1NC(=O)c2cc3ccc(cc3n2[C@@H]1C)C(=O)Nc1cc(C)on1

InChI Key: InChIKey=AMQAOXDPHJIPPA-WDEREUQCSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184295   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha 2 (Homo sapiens (Human))	BDBM184295 (US9150577, 171) Show SMILES C[C@@H]1NC(=O)c2cc3ccc(cc3n2[C@@H]1C)C(=O)Nc1cc(C)on1 |r| Show InChI InChI=1S/C18H18N4O3/c1-9-6-16(21-25-9)20-17(23)13-5-4-12-7-15-18(24)19-10(2)11(3)22(15)14(12)8-13/h4-8,10-11H,1-3H3,(H,19,24)(H,20,21,23)/t10-,11+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...				US Patent US9150577 (2015) BindingDB Entry DOI: 10.7270/Q2GB22V6
					More data for this Ligand-Target Pair