BDBM18442 4-[benzene(methyl)sulfonamido]-N-(5-methyl-1,2-oxazol-3-yl)benzamide::Sulfonamide analogue, 13

SMILES: CN(c1ccc(cc1)C(=O)Nc1cc(C)on1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=RBQWPZZOSRJEKA-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM18442 (4-[benzene(methyl)sulfonamido]-N-(5-methyl-1,2-oxa...) Show SMILES CN(c1ccc(cc1)C(=O)Nc1cc(C)on1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H17N3O4S/c1-13-12-17(20-25-13)19-18(22)14-8-10-15(11-9-14)21(2)26(23,24)16-6-4-3-5-7-16/h3-12H,1-2H3,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.92E+4	-6.34	2.52E+4	n/a	n/a	n/a	n/a	5.9	21
NIH					Assay Description Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...				Proc Natl Acad Sci U S A 104: 13192-7 (2007) Article DOI: 10.1073/pnas.0705637104 BindingDB Entry DOI: 10.7270/Q2V1232M
					More data for this Ligand-Target Pair