BDBM184848 US9156811, DDD85646

SMILES: Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1

InChI Key: InChIKey=MCLKNJADSXFFOA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 184848   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-myristoyltransferase (NMT1) (Trypanosoma brucei)	BDBM184848 (US9156811, DDD85646) Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24H,6-9H2,1-3H3,(H-,27,30,31)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
N-myristoyltransferase (NMT1) (Aspergillus fumigatus)	BDBM184848 (US9156811, DDD85646) Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24H,6-9H2,1-3H3,(H-,27,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Homo sapiens (Human))	BDBM184848 (US9156811, DDD85646) Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24H,6-9H2,1-3H3,(H-,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair