BDBM185023 US9156811, DDD99759

SMILES: Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl

InChI Key: InChIKey=WKXJMUPONLJJAH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Homo sapiens (Human))	BDBM185023 (US9156811, DDD99759) Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl Show InChI InChI=1S/C20H28Cl2N4O2S/c1-13-19(14(2)26(3)24-13)25-29(27,28)20-17(21)11-16(12-18(20)22)6-4-5-15-7-9-23-10-8-15/h11-12,15,23H,4-10H2,1-3H3,(H-,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
N-myristoyltransferase (NMT1) (Trypanosoma brucei)	BDBM185023 (US9156811, DDD99759) Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl Show InChI InChI=1S/C20H28Cl2N4O2S/c1-13-19(14(2)26(3)24-13)25-29(27,28)20-17(21)11-16(12-18(20)22)6-4-5-15-7-9-23-10-8-15/h11-12,15,23H,4-10H2,1-3H3,(H-,25,27,28)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair