BDBM185054 US9156811, DDD100096

SMILES: Cc1nn(C)c(C)c1N(C(F)F)[S+]([O-])(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl

InChI Key: InChIKey=WZELAXINRXHZED-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Homo sapiens (Human))	BDBM185054 (US9156811, DDD100096) Show SMILES Cc1nn(C)c(C)c1N(C(F)F)[S+]([O-])(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl Show InChI InChI=1S/C21H28Cl2F2N4O2S/c1-13-19(14(2)28(3)27-13)29(21(24)25)32(30,31)20-17(22)11-16(12-18(20)23)6-4-5-15-7-9-26-10-8-15/h11-12,15,21,26H,4-10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
N-myristoyltransferase (NMT1) (Trypanosoma brucei)	BDBM185054 (US9156811, DDD100096) Show SMILES Cc1nn(C)c(C)c1N(C(F)F)[S+]([O-])(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl Show InChI InChI=1S/C21H28Cl2F2N4O2S/c1-13-19(14(2)28(3)27-13)29(21(24)25)32(30,31)20-17(22)11-16(12-18(20)23)6-4-5-15-7-9-26-10-8-15/h11-12,15,21,26H,4-10H2,1-3H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair