BDBM185180 [2-[[2-(4-tert-Butoxycarbonylpiperazin-1-yl)-2-oxo-ethyl]amino]-2-oxo-ethyl]-dimethylsulfonium bromide (1m)

SMILES: C[S+](C)CC(=O)NCC(=O)N1CCN(CC1)C(=O)OC(C)(C)C

InChI Key: InChIKey=YJDVPKRUTWXJJT-UHFFFAOYSA-O

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 185180   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-glutamine gamma-glutamyltransferase 2 (TG2) (Homo sapiens (Human))	BDBM185180 ([2-[[2-(4-tert-Butoxycarbonylpiperazin-1-yl)-2-oxo...) Show SMILES C[S+](C)CC(=O)NCC(=O)N1CCN(CC1)C(=O)OC(C)(C)C Show InChI InChI=1S/C15H27N3O4S/c1-15(2,3)22-14(21)18-8-6-17(7-9-18)13(20)10-16-12(19)11-23(4)5/h6-11H2,1-5H3/p+1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	273	n/a	n/a	n/a	n/a	n/a	n/a
Aston University					Assay Description For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...				Chem Biol 22: 1347-61 (2015) Article DOI: 10.1016/j.chembiol.2015.08.013 BindingDB Entry DOI: 10.7270/Q2222SJC
					More data for this Ligand-Target Pair
Coagulation factor XIII A (FXIIIa) (Homo sapiens (Human))	BDBM185180 ([2-[[2-(4-tert-Butoxycarbonylpiperazin-1-yl)-2-oxo...) Show SMILES C[S+](C)CC(=O)NCC(=O)N1CCN(CC1)C(=O)OC(C)(C)C Show InChI InChI=1S/C15H27N3O4S/c1-15(2,3)22-14(21)18-8-6-17(7-9-18)13(20)10-16-12(19)11-23(4)5/h6-11H2,1-5H3/p+1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Aston University					Assay Description For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...				Chem Biol 22: 1347-61 (2015) Article DOI: 10.1016/j.chembiol.2015.08.013 BindingDB Entry DOI: 10.7270/Q2222SJC
					More data for this Ligand-Target Pair
Transglutaminase-3 (TG3) (Homo sapiens (Human))	BDBM185180 ([2-[[2-(4-tert-Butoxycarbonylpiperazin-1-yl)-2-oxo...) Show SMILES C[S+](C)CC(=O)NCC(=O)N1CCN(CC1)C(=O)OC(C)(C)C Show InChI InChI=1S/C15H27N3O4S/c1-15(2,3)22-14(21)18-8-6-17(7-9-18)13(20)10-16-12(19)11-23(4)5/h6-11H2,1-5H3/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Aston University					Assay Description For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...				Chem Biol 22: 1347-61 (2015) Article DOI: 10.1016/j.chembiol.2015.08.013 BindingDB Entry DOI: 10.7270/Q2222SJC
					More data for this Ligand-Target Pair
Transglutaminase-1 (TG1) (Homo sapiens (Human))	BDBM185180 ([2-[[2-(4-tert-Butoxycarbonylpiperazin-1-yl)-2-oxo...) Show SMILES C[S+](C)CC(=O)NCC(=O)N1CCN(CC1)C(=O)OC(C)(C)C Show InChI InChI=1S/C15H27N3O4S/c1-15(2,3)22-14(21)18-8-6-17(7-9-18)13(20)10-16-12(19)11-23(4)5/h6-11H2,1-5H3/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Aston University					Assay Description For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...				Chem Biol 22: 1347-61 (2015) Article DOI: 10.1016/j.chembiol.2015.08.013 BindingDB Entry DOI: 10.7270/Q2222SJC
					More data for this Ligand-Target Pair