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SMILES: COc1ccc(cc1-c1c[nH]c2ncnc(N(C)C)c12)[N+]#[C-]

InChI Key: InChIKey=DFQYQGOPAOYWOZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM185381 (US9156845, 24) Show SMILES COc1ccc(cc1-c1c[nH]c2ncnc(N(C)C)c12)[N+]#[C-] Show InChI InChI=1S/C16H15N5O/c1-17-10-5-6-13(22-4)11(7-10)12-8-18-15-14(12)16(21(2)3)20-9-19-15/h5-9H,2-4H3,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	7.5	n/a
Pfizer Inc. US Patent					Assay Description LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat # PV4874) was incu...				US Patent US9156845 (2015) BindingDB Entry DOI: 10.7270/Q2DB80MW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM185381 (US9156845, 24) Show SMILES COc1ccc(cc1-c1c[nH]c2ncnc(N(C)C)c12)[N+]#[C-] Show InChI InChI=1S/C16H15N5O/c1-17-10-5-6-13(22-4)11(7-10)12-8-18-15-14(12)16(21(2)3)20-9-19-15/h5-9H,2-4H3,(H,18,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.5	n/a
Pfizer Inc. US Patent					Assay Description LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat # PV4874) was incu...				US Patent US9156845 (2015) BindingDB Entry DOI: 10.7270/Q2DB80MW
					More data for this Ligand-Target Pair