BDBM18562 6-alkyl, 7-amino-2-quinolinone, 11d (+/-)::7-amino-6-(butan-2-yl)-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one

SMILES: CCC(C)c1cc2c(cc(=O)[nH]c2cc1N)C(F)(F)F

InChI Key: InChIKey=YUWKVMXGTKIENL-UHFFFAOYSA-N

Data: 1 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM18562 (6-alkyl, 7-amino-2-quinolinone, 11d (+/-) | 7-amin...) Show SMILES CCC(C)c1cc2c(cc(=O)[nH]c2cc1N)C(F)(F)F Show InChI InChI=1S/C14H15F3N2O/c1-3-7(2)8-4-9-10(14(15,16)17)5-13(20)19-12(9)6-11(8)18/h4-7H,3,18H2,1-2H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	13	n/a	14	n/a	65	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc.					Assay Description The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...				Bioorg Med Chem Lett 17: 1523-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.007 BindingDB Entry DOI: 10.7270/Q22J6950
					More data for this Ligand-Target Pair