null

SMILES: Cc1nc(Nc2ncc(s2)C(=O)Nc2ccc(Oc3ccccc3)cc2C)cc(n1)N1CCN(CCO)CC1

InChI Key: InChIKey=YNYJXKOBWFTYSQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185673   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 [229-512] (Homo sapiens (Human))	BDBM185673 (DAS-CHO-II) Show SMILES Cc1nc(Nc2ncc(s2)C(=O)Nc2ccc(Oc3ccccc3)cc2C)cc(n1)N1CCN(CCO)CC1 Show InChI InChI=1S/C28H31N7O3S/c1-19-16-22(38-21-6-4-3-5-7-21)8-9-23(19)32-27(37)24-18-29-28(39-24)33-25-17-26(31-20(2)30-25)35-12-10-34(11-13-35)14-15-36/h3-9,16-18,36H,10-15H2,1-2H3,(H,32,37)(H,29,30,31,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a
Stony Brook University					Assay Description Inhibitor selectivity profiles were obtained through Luceome Biotechnologies (Tuscon, AZ). Each inhibitor was screened at 0.5 μM against a panel...				ACS Chem Biol 11: 1296-304 (2016) Article DOI: 10.1021/acschembio.5b01018 BindingDB Entry DOI: 10.7270/Q2MW2FXD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src [251-533] (Gallus gallus (Chicken))	BDBM185673 (DAS-CHO-II) Show SMILES Cc1nc(Nc2ncc(s2)C(=O)Nc2ccc(Oc3ccccc3)cc2C)cc(n1)N1CCN(CCO)CC1 Show InChI InChI=1S/C28H31N7O3S/c1-19-16-22(38-21-6-4-3-5-7-21)8-9-23(19)32-27(37)24-18-29-28(39-24)33-25-17-26(31-20(2)30-25)35-12-10-34(11-13-35)14-15-36/h3-9,16-18,36H,10-15H2,1-2H3,(H,32,37)(H,29,30,31,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a
Stony Brook University					Assay Description Inhibitor selectivity profiles were obtained through Luceome Biotechnologies (Tuscon, AZ). Each inhibitor was screened at 0.5 μM against a panel...				ACS Chem Biol 11: 1296-304 (2016) Article DOI: 10.1021/acschembio.5b01018 BindingDB Entry DOI: 10.7270/Q2MW2FXD
					More data for this Ligand-Target Pair