BDBM18570 6-(ethylamino)-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one::6-alkylamino 2-quinolinone, 13b

SMILES: CCNc1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F

InChI Key: InChIKey=UJYRQBRFTFDTGJ-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM18570 (6-(ethylamino)-4-(trifluoromethyl)-1,2-dihydroquin...) Show SMILES CCNc1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F Show InChI InChI=1S/C12H11F3N2O/c1-2-16-7-3-4-10-8(5-7)9(12(13,14)15)6-11(18)17-10/h3-6,16H,2H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc.					Assay Description The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...				Bioorg Med Chem Lett 17: 1523-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.007 BindingDB Entry DOI: 10.7270/Q22J6950
					More data for this Ligand-Target Pair