BDBM18573 6-(cyclopentylamino)-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one::6-alkylamino 2-quinolinone, 13e

SMILES: FC(F)(F)c1cc(=O)[nH]c2ccc(NC3CCCC3)cc12

InChI Key: InChIKey=WUSYUUHWBCIJBB-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM18573 (6-(cyclopentylamino)-4-(trifluoromethyl)-1,2-dihyd...) Show SMILES FC(F)(F)c1cc(=O)[nH]c2ccc(NC3CCCC3)cc12 Show InChI InChI=1S/C15H15F3N2O/c16-15(17,18)12-8-14(21)20-13-6-5-10(7-11(12)13)19-9-3-1-2-4-9/h5-9,19H,1-4H2,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	74	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc.					Assay Description The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...				Bioorg Med Chem Lett 17: 1523-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.007 BindingDB Entry DOI: 10.7270/Q22J6950
					More data for this Ligand-Target Pair