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SMILES: Fc1c(F)c(F)c(Cn2cc(nn2)C(=O)\C=C\c2ccc(cc2)N(=O)=O)c(F)c1F

InChI Key: InChIKey=SQAGYNCQYWDUNQ-ZZXKWVIFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 185763   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein-glutamine gamma-glutamyltransferase 2


(Cavia cutleri (Guinea pig))		BDBM185763
PNG
(US9162991, 4i)
Show SMILES Fc1c(F)c(F)c(Cn2cc(nn2)C(=O)\C=C\c2ccc(cc2)N(=O)=O)c(F)c1F
Show InChI InChI=1S/C18H9F5N4O3/c19-14-11(15(20)17(22)18(23)16(14)21)7-26-8-12(24-25-26)13(28)6-3-9-1-4-10(5-2-9)27(29)30/h1-6,8H,7H2/b6-3+
UniProtKB/SwissProt

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Similars
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Ottawa

US Patent


Assay Description
For enzymology studies of these compounds, recombinant guinea pig liver TGase was expressed in Escherichia coli and effectively purified (Gillet, S. ...

US Patent US9162991 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X8J
More data for this
Ligand-Target Pair