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BDBM185763 US9162991, 4i

SMILES: Fc1c(F)c(F)c(Cn2cc(nn2)C(=O)\C=C\c2ccc(cc2)N(=O)=O)c(F)c1F

InChI Key: InChIKey=SQAGYNCQYWDUNQ-ZZXKWVIFSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 185763   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transglutaminases (TGase)


(Cavia cutleri (Guinea pig))
BDBM185763
PNG
(US9162991, 4i)
Show SMILES Fc1c(F)c(F)c(Cn2cc(nn2)C(=O)\C=C\c2ccc(cc2)N(=O)=O)c(F)c1F
Show InChI InChI=1S/C18H9F5N4O3/c19-14-11(15(20)17(22)18(23)16(14)21)7-26-8-12(24-25-26)13(28)6-3-9-1-4-10(5-2-9)27(29)30/h1-6,8H,7H2/b6-3+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Ottawa

US Patent


Assay Description
For enzymology studies of these compounds, recombinant guinea pig liver TGase was expressed in Escherichia coli and effectively purified (Gillet, S. ...


US Patent US9162991 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X8J
More data for this
Ligand-Target Pair