BDBM185878 US9163007, 263

SMILES: NC(=O)N(c1n[nH]c2ccc(cc12)-c1nnn(Cc2ccccc2)c1C1CC1)c1ccccc1Cl

InChI Key: InChIKey=ILXKCOULKWPNBJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 185878   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM185878 (US9163007, 263) Show SMILES NC(=O)N(c1n[nH]c2ccc(cc12)-c1nnn(Cc2ccccc2)c1C1CC1)c1ccccc1Cl Show InChI InChI=1S/C26H22ClN7O/c27-20-8-4-5-9-22(20)34(26(28)35)25-19-14-18(12-13-21(19)29-31-25)23-24(17-10-11-17)33(32-30-23)15-16-6-2-1-3-7-16/h1-9,12-14,17H,10-11,15H2,(H2,28,35)(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	22	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description 11 data point. Cdc7 kinase assays were carried out in 25 mM HEPES, pH 7.5, 1 mM DTT, 10 mM MgCl2, 100 μM Na3VO4, and 0.075 mg/ml Triton X-100 u...				US Patent US9163007 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DTG
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