BDBM185906 US9163007, 413

SMILES: COc1ccc(CNc2n[nH]c3ccc(cc23)-c2cn(Cc3ccccc3)nn2)cc1

InChI Key: InChIKey=CWGMLORJXNUQPL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 185906   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM185906 (US9163007, 413) Show SMILES COc1ccc(CNc2n[nH]c3ccc(cc23)-c2cn(Cc3ccccc3)nn2)cc1 Show InChI InChI=1S/C24H22N6O/c1-31-20-10-7-17(8-11-20)14-25-24-21-13-19(9-12-22(21)26-28-24)23-16-30(29-27-23)15-18-5-3-2-4-6-18/h2-13,16H,14-15H2,1H3,(H2,25,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	52	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description 11 data point. Cdc7 kinase assays were carried out in 25 mM HEPES, pH 7.5, 1 mM DTT, 10 mM MgCl2, 100 μM Na3VO4, and 0.075 mg/ml Triton X-100 u...				US Patent US9163007 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DTG
					More data for this Ligand-Target Pair