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SMILES: CCN(Cc1ccoc1)c1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F

InChI Key: InChIKey=JVVRHHHFMUUTLW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18598   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Androgen receptor


(Homo sapiens (Human))		BDBM18598
PNG
(6-[ethyl(furan-3-ylmethyl)amino]-4-(trifluoromethy...)
Show SMILES CCN(Cc1ccoc1)c1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F
Show InChI InChI=1S/C17H15F3N2O2/c1-2-22(9-11-5-6-24-10-11)12-3-4-15-13(7-12)14(17(18,19)20)8-16(23)21-15/h3-8,10H,2,9H2,1H3,(H,21,23)
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MMDB

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KEGG

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Article
PubMed
 14n/an/an/a 2.80n/an/an/an/a



Ligand Pharmaceuticals Inc.



Assay Description
The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...

Bioorg Med Chem Lett 17: 1527-31 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.001
BindingDB Entry DOI: 10.7270/Q2XS5SP9
More data for this
Ligand-Target Pair