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BDBM18600 6-[bis(2,2,2-trifluoroethyl)amino]-1,2-dihydroquinolin-2-one::6-bisalkylamino-2-quinolinone, 7a

SMILES: FC(F)(F)CN(CC(F)(F)F)c1ccc2[nH]c(=O)ccc2c1

InChI Key: InChIKey=FWWVTQIQPUIKFW-UHFFFAOYSA-N

Data: 1 KI  1 IC50  1 EC50

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18600   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Androgen Receptor


(Homo sapiens (Human))
BDBM18600
PNG
(6-[bis(2,2,2-trifluoroethyl)amino]-1,2-dihydroquin...)
Show SMILES FC(F)(F)CN(CC(F)(F)F)c1ccc2[nH]c(=O)ccc2c1
Show InChI InChI=1S/C13H10F6N2O/c14-12(15,16)6-21(7-13(17,18)19)9-2-3-10-8(5-9)1-4-11(22)20-10/h1-5H,6-7H2,(H,20,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
24n/a 1n/a 57n/an/an/an/a



Ligand Pharmaceuticals Inc.



Assay Description
The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...


Bioorg Med Chem Lett 17: 1527-31 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.001
BindingDB Entry DOI: 10.7270/Q2XS5SP9
More data for this
Ligand-Target Pair