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BDBM18603 6-[bis(2,2,2-trifluoroethyl)amino]-4-propyl-1,2-dihydroquinolin-2-one::6-bisalkylamino-2-quinolinone, 7d

SMILES: CCCc1cc(=O)[nH]c2ccc(cc12)N(CC(F)(F)F)CC(F)(F)F

InChI Key: InChIKey=CFNJVXQDHLLLEQ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18603   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Androgen Receptor


(Homo sapiens (Human))
BDBM18603
PNG
(6-[bis(2,2,2-trifluoroethyl)amino]-4-propyl-1,2-di...)
Show SMILES CCCc1cc(=O)[nH]c2ccc(cc12)N(CC(F)(F)F)CC(F)(F)F
Show InChI InChI=1S/C16H16F6N2O/c1-2-3-10-6-14(25)23-13-5-4-11(7-12(10)13)24(8-15(17,18)19)9-16(20,21)22/h4-7H,2-3,8-9H2,1H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
42n/a 36n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc.



Assay Description
The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...


Bioorg Med Chem Lett 17: 1527-31 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.001
BindingDB Entry DOI: 10.7270/Q2XS5SP9
More data for this
Ligand-Target Pair