BDBM186936 US9079895, 24s

SMILES: COc1cccc(OC[C@@H]2CN(CC(=O)N3CCc4ccccc34)CCO2)c1

InChI Key: InChIKey=KJWABLDVLWKPKR-FQEVSTJZSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 186936   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (5HT1A) (Mus musculus (Mouse))	BDBM186936 (US9079895, 24s) Show SMILES COc1cccc(OC[C@@H]2CN(CC(=O)N3CCc4ccccc34)CCO2)c1 |r| Show InChI InChI=1S/C22H26N2O4/c1-26-18-6-4-7-19(13-18)28-16-20-14-23(11-12-27-20)15-22(25)24-10-9-17-5-2-3-8-21(17)24/h2-8,13,20H,9-12,14-16H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	371	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Dundee US Patent					Assay Description The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...				US Patent US9079895 (2015) BindingDB Entry DOI: 10.7270/Q2D7996K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (5HT2B) (Mus musculus (Mouse))	BDBM186936 (US9079895, 24s) Show SMILES COc1cccc(OC[C@@H]2CN(CC(=O)N3CCc4ccccc34)CCO2)c1 |r| Show InChI InChI=1S/C22H26N2O4/c1-26-18-6-4-7-19(13-18)28-16-20-14-23(11-12-27-20)15-22(25)24-10-9-17-5-2-3-8-21(17)24/h2-8,13,20H,9-12,14-16H2,1H3/t20-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Dundee US Patent					Assay Description The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...				US Patent US9079895 (2015) BindingDB Entry DOI: 10.7270/Q2D7996K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (5HT2A) (Mus musculus (Mouse))	BDBM186936 (US9079895, 24s) Show SMILES COc1cccc(OC[C@@H]2CN(CC(=O)N3CCc4ccccc34)CCO2)c1 |r| Show InChI InChI=1S/C22H26N2O4/c1-26-18-6-4-7-19(13-18)28-16-20-14-23(11-12-27-20)15-22(25)24-10-9-17-5-2-3-8-21(17)24/h2-8,13,20H,9-12,14-16H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Dundee US Patent					Assay Description The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...				US Patent US9079895 (2015) BindingDB Entry DOI: 10.7270/Q2D7996K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (5HT1B) (Mus musculus (Mouse))	BDBM186936 (US9079895, 24s) Show SMILES COc1cccc(OC[C@@H]2CN(CC(=O)N3CCc4ccccc34)CCO2)c1 |r| Show InChI InChI=1S/C22H26N2O4/c1-26-18-6-4-7-19(13-18)28-16-20-14-23(11-12-27-20)15-22(25)24-10-9-17-5-2-3-8-21(17)24/h2-8,13,20H,9-12,14-16H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.83E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Dundee US Patent					Assay Description The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...				US Patent US9079895 (2015) BindingDB Entry DOI: 10.7270/Q2D7996K
					More data for this Ligand-Target Pair