null

SMILES: CCCCCCCc1ccc(cc1)C(=O)C=CC

InChI Key: InChIKey=LCSOCUYXJADQCV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18827   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor beta [209-461] (Homo sapiens (Human))	BDBM18827 ((2E)-1-(4-heptylphenyl)but-2-en-1-one | Enone, 4b) Show SMILES CCCCCCCc1ccc(cc1)C(=O)C=CC |w:16.17| Show InChI InChI=1S/C17H24O/c1-3-5-6-7-8-10-15-11-13-16(14-12-15)17(18)9-4-2/h4,9,11-14H,3,5-8,10H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Research Hospital					Assay Description IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...				J Med Chem 50: 5269-5280 (2007) Article DOI: 10.1021/jm070556y BindingDB Entry DOI: 10.7270/Q24B2ZK8
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha [148-410] (Homo sapiens (Human))	BDBM18827 ((2E)-1-(4-heptylphenyl)but-2-en-1-one | Enone, 4b) Show SMILES CCCCCCCc1ccc(cc1)C(=O)C=CC |w:16.17| Show InChI InChI=1S/C17H24O/c1-3-5-6-7-8-10-15-11-13-16(14-12-15)17(18)9-4-2/h4,9,11-14H,3,5-8,10H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a	7.2	22
St. Jude Research Hospital					Assay Description IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...				J Med Chem 50: 5269-5280 (2007) Article DOI: 10.1021/jm070556y BindingDB Entry DOI: 10.7270/Q24B2ZK8
					More data for this Ligand-Target Pair