null

SMILES: C=CCn1c(NS(=O)(=O)c2ccccc2)c(C#N)c2nc3ccccc3nc12

InChI Key: InChIKey=FESFSIJRTMDEFH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 188307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (Mycobacterium tuberculosis)	BDBM188307 (US9073941, 1002) Show SMILES C=CCn1c(NS(=O)(=O)c2ccccc2)c(C#N)c2nc3ccccc3nc12 Show InChI InChI=1S/C20H15N5O2S/c1-2-12-25-19(24-28(26,27)14-8-4-3-5-9-14)15(13-21)18-20(25)23-17-11-7-6-10-16(17)22-18/h2-11,24H,1,12H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.32E+3	n/a	n/a	n/a	n/a	7.0	n/a
Academia Sinica US Patent					Assay Description Mtb PDH (Lpd+DlaT+AceE) is provided by Dr. Bryk Ruslana. The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (...				US Patent US9073941 (2015) BindingDB Entry DOI: 10.7270/Q2HX1BGC
					More data for this Ligand-Target Pair
Dihydrolipoyl dehydrogenase (Mycobacterium tuberculosis)	BDBM188307 (US9073941, 1002) Show SMILES C=CCn1c(NS(=O)(=O)c2ccccc2)c(C#N)c2nc3ccccc3nc12 Show InChI InChI=1S/C20H15N5O2S/c1-2-12-25-19(24-28(26,27)14-8-4-3-5-9-14)15(13-21)18-20(25)23-17-11-7-6-10-16(17)22-18/h2-11,24H,1,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	980	n/a	n/a	n/a	n/a	7.0	n/a
Academia Sinica US Patent					Assay Description The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...				US Patent US9073941 (2015) BindingDB Entry DOI: 10.7270/Q2HX1BGC
					More data for this Ligand-Target Pair