BDBM18831 (2E)-1-(4-heptylphenyl)-3-phenylprop-2-en-1-one::Enone, 4f
SMILES: CCCCCCCc1ccc(cc1)C(=O)\C=C\c1ccccc1
InChI Key: InChIKey=IYQXHSFSCRDACY-OBGWFSINSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thyroid hormone receptor beta [209-461] (Homo sapiens (Human)) | BDBM18831 ((2E)-1-(4-heptylphenyl)-3-phenylprop-2-en-1-one | ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Research Hospital | Assay Description IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari... | J Med Chem 50: 5269-5280 (2007) Article DOI: 10.1021/jm070556y BindingDB Entry DOI: 10.7270/Q24B2ZK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor alpha [148-410] (Homo sapiens (Human)) | BDBM18831 ((2E)-1-(4-heptylphenyl)-3-phenylprop-2-en-1-one | ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.2 | 22 |
St. Jude Research Hospital | Assay Description IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari... | J Med Chem 50: 5269-5280 (2007) Article DOI: 10.1021/jm070556y BindingDB Entry DOI: 10.7270/Q24B2ZK8 | |||||||||||
More data for this Ligand-Target Pair |