BDBM188545 US9169246, 30

SMILES: FC(F)(F)Cn1c2cc(ccc2c2[nH]ncc2c1=O)-c1ccc(cc1)N1CCNCC1

InChI Key: InChIKey=YAXAVGNETMJPHS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM188545 (US9169246, 30) Show SMILES FC(F)(F)Cn1c2cc(ccc2c2[nH]ncc2c1=O)-c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C22H20F3N5O/c23-22(24,25)13-30-19-11-15(3-6-17(19)20-18(21(30)31)12-27-28-20)14-1-4-16(5-2-14)29-9-7-26-8-10-29/h1-6,11-12,26H,7-10,13H2,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.13	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...				US Patent US9169246 (2015) BindingDB Entry DOI: 10.7270/Q2B856XZ
					More data for this Ligand-Target Pair