null
SMILES: CC(=O)N1CCC(C)(c2ccccc2)c2cc(NC(=O)OCc3ccc(F)c(Cl)c3)ccc12
InChI Key: InChIKey=IRWJUAWYXLTKDV-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thyrotropin receptor (Homo sapiens (Human)) | BDBM189329 ((+)-(1-Acetyl-4-methyl-4-phenyl-1,2,3,4-tetrahydro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyrotropin subunit beta (Bos taurus (Bovine)) | BDBM189329 ((+)-(1-Acetyl-4-methyl-4-phenyl-1,2,3,4-tetrahydro...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 192 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ... | US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC | |||||||||||
More data for this Ligand-Target Pair |