BDBM189340 STOCK5S-55040 (5)

SMILES: CCOc1ccc(cc1)N1CC(O)Cn2c1nc1n(C)c(=O)n(CC(N)=O)c(=O)c21

InChI Key: InChIKey=DTTORPYIUBJLGY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 189340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Capsid Protein) (Human immunodeficiency virus type 1 group M subtyp...)	BDBM189340 (STOCK5S-55040 (5)) Show SMILES CCOc1ccc(cc1)N1CC(O)Cn2c1nc1n(C)c(=O)n(CC(N)=O)c(=O)c21 Show InChI InChI=1S/C19H22N6O5/c1-3-30-13-6-4-11(5-7-13)23-8-12(26)9-24-15-16(21-18(23)24)22(2)19(29)25(17(15)28)10-14(20)27/h4-7,12,26H,3,8-10H2,1-2H3,(H2,20,27)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.8	37
University of Siena					Assay Description HIV RT-associated RNase H activity was measured as previously described.[J. Med. Chem. 2014, 57:3223-3234] Briefly, the reaction mixture comprised ...				Chembiochem 17: 683-8 (2016) Article DOI: 10.1002/cbic.201500668 BindingDB Entry DOI: 10.7270/Q25H7F28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein) (Human immunodeficiency virus type 1 group M subtyp...)	BDBM189340 (STOCK5S-55040 (5)) Show SMILES CCOc1ccc(cc1)N1CC(O)Cn2c1nc1n(C)c(=O)n(CC(N)=O)c(=O)c21 Show InChI InChI=1S/C19H22N6O5/c1-3-30-13-6-4-11(5-7-13)23-8-12(26)9-24-15-16(21-18(23)24)22(2)19(29)25(17(15)28)10-14(20)27/h4-7,12,26H,3,8-10H2,1-2H3,(H2,20,27)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.1	37
University of Siena					Assay Description RNA-dependent DNA polymerase (RDDP) activity was measured as described[J. Microbiol. 2015, 53:288-293] in Tris·HCl buffer (25 mL, 60 mm, pH 8.1) con...				Chembiochem 17: 683-8 (2016) Article DOI: 10.1002/cbic.201500668 BindingDB Entry DOI: 10.7270/Q25H7F28
					More data for this Ligand-Target Pair