BDBM189341 STOCK4S-60534 (6)

SMILES: CCOc1ccc(cc1)N1CC(O)Cn2c1nc1n(C)c(=O)n(CC(=O)OCc3ccccc3)c(=O)c21

InChI Key: InChIKey=KQLREHFTDRTJCM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 189341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Capsid Protein) (Human immunodeficiency virus type 1 group M subtyp...)	BDBM189341 (STOCK4S-60534 (6)) Show SMILES CCOc1ccc(cc1)N1CC(O)Cn2c1nc1n(C)c(=O)n(CC(=O)OCc3ccccc3)c(=O)c21 Show InChI InChI=1S/C26H27N5O6/c1-3-36-20-11-9-18(10-12-20)29-13-19(32)14-30-22-23(27-25(29)30)28(2)26(35)31(24(22)34)15-21(33)37-16-17-7-5-4-6-8-17/h4-12,19,32H,3,13-16H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	7.8	37
University of Siena					Assay Description HIV RT-associated RNase H activity was measured as previously described.[J. Med. Chem. 2014, 57:3223-3234] Briefly, the reaction mixture comprised ...				Chembiochem 17: 683-8 (2016) Article DOI: 10.1002/cbic.201500668 BindingDB Entry DOI: 10.7270/Q25H7F28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein) (Human immunodeficiency virus type 1 group M subtyp...)	BDBM189341 (STOCK4S-60534 (6)) Show SMILES CCOc1ccc(cc1)N1CC(O)Cn2c1nc1n(C)c(=O)n(CC(=O)OCc3ccccc3)c(=O)c21 Show InChI InChI=1S/C26H27N5O6/c1-3-36-20-11-9-18(10-12-20)29-13-19(32)14-30-22-23(27-25(29)30)28(2)26(35)31(24(22)34)15-21(33)37-16-17-7-5-4-6-8-17/h4-12,19,32H,3,13-16H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.85E+4	n/a	n/a	n/a	n/a	8.1	37
University of Siena					Assay Description RNA-dependent DNA polymerase (RDDP) activity was measured as described[J. Microbiol. 2015, 53:288-293] in Tris·HCl buffer (25 mL, 60 mm, pH 8.1) con...				Chembiochem 17: 683-8 (2016) Article DOI: 10.1002/cbic.201500668 BindingDB Entry DOI: 10.7270/Q25H7F28
					More data for this Ligand-Target Pair