BDBM189344 (3-Chlorophenyl)(4-methylpiperazin-1-yl)methanone (2)

SMILES: CN1CCN(CC1)C(=O)c1cccc(Cl)c1

InChI Key: InChIKey=JMCVROBSFMMHPI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189344   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM189344 ((3-Chlorophenyl)(4-methylpiperazin-1-yl)methanone ...) Show SMILES CN1CCN(CC1)C(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C12H15ClN2O/c1-14-5-7-15(8-6-14)12(16)10-3-2-4-11(13)9-10/h2-4,9H,5-8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.88E+3	-6.86	n/a	n/a	n/a	n/a	n/a	7.4	4
Jagiellonian University Medical College					Assay Description Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...				Chem Biol Drug Des 88: 254-63 (2016) Article DOI: 10.1111/cbdd.12752 BindingDB Entry DOI: 10.7270/Q21R6P93
					More data for this Ligand-Target Pair