BDBM189359 SRI35566

SMILES: O=C1CC(c2ccccc2)c2c(N1)n1ncnc1[nH]c2=O

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189359   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitotic kinesin Eg5 (Eg5) (Homo sapiens (Human))	BDBM189359 (SRI35566) Show SMILES O=C1CC(c2ccccc2)c2c(N1)n1ncnc1[nH]c2=O Show InChI	PDB GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	7.0	25
Southern Research Institute					Assay Description Compounds were first tested in triplicates at 100 uM; hit compounds were further tested with a 10-point twofold serial dilution to confirm their acti...				Chem Biol Drug Des 88: 178-87 (2016) Article DOI: 10.1111/cbdd.12744 BindingDB Entry DOI: 10.7270/Q2NK3CV8
					More data for this Ligand-Target Pair