BDBM189359 SRI35566
SMILES: O=C1CC(c2ccccc2)c2c(N1)n1ncnc1[nH]c2=O
InChI Key:
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitotic kinesin Eg5 (Eg5) (Homo sapiens (Human)) | BDBM189359 (SRI35566) | PDB GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Southern Research Institute | Assay Description Compounds were first tested in triplicates at 100 uM; hit compounds were further tested with a 10-point twofold serial dilution to confirm their acti... | Chem Biol Drug Des 88: 178-87 (2016) Article DOI: 10.1111/cbdd.12744 BindingDB Entry DOI: 10.7270/Q2NK3CV8 | |||||||||||
More data for this Ligand-Target Pair |