BDBM189361 SRI35564
SMILES: Cc1ccc(cc1)C1C(C#N)=C(N)Nc2ncnn12
InChI Key: InChIKey=YISIIJDKYGEHIN-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitotic kinesin Eg5 (Eg5) (Homo sapiens (Human)) | BDBM189361 (SRI35564) | PDB GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.18E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Southern Research Institute | Assay Description Compounds were first tested in triplicates at 100 uM; hit compounds were further tested with a 10-point twofold serial dilution to confirm their acti... | Chem Biol Drug Des 88: 178-87 (2016) Article DOI: 10.1111/cbdd.12744 BindingDB Entry DOI: 10.7270/Q2NK3CV8 | |||||||||||
More data for this Ligand-Target Pair |