BDBM190607 US9181230, 13
SMILES: Fc1ccc(-c2cc(n[nH]2)-c2ccc(cc2)[C@H]2CNCCO2)c(F)c1
InChI Key:
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trace amine-associated receptor 1 (TAAR1) (Mus musculus (Mouse)) | BDBM190607 (US9181230, 13) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.300 | -13.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h... | US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (TAAR1) (Rattus norvegicus (Rat)) | BDBM190607 (US9181230, 13) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 30.5 | -10.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h... | US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z | |||||||||||
More data for this Ligand-Target Pair |