BDBM190690 US9181233, 67
SMILES: COc1ccc(SCc2nnc(s2)-c2ccc3[nH]cnc3c2)cc1OC
InChI Key: InChIKey=ZONFSXMNDBXNOQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutaminyl Cyclase (Homo sapiens (Human)) | BDBM190690 (US9181233, 67) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 10 | -11.1 | 80 | n/a | n/a | n/a | n/a | n/a | 30 |
PROBIODRUG AG US Patent | Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ... | US Patent US9181233 (2015) BindingDB Entry DOI: 10.7270/Q2S46QQH | |||||||||||
More data for this Ligand-Target Pair |