null

SMILES: NC(=O)c1ccc(cc1)-c1c(cc2C(=O)NCC(CCO)n12)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=ZBDQLRFROCVCJP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191089   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM191089 (US9181258, 77) Show SMILES NC(=O)c1ccc(cc1)-c1c(cc2C(=O)NCC(CCO)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H20F3N3O4/c24-23(25,26)33-17-3-1-2-15(10-17)18-11-19-22(32)28-12-16(8-9-30)29(19)20(18)13-4-6-14(7-5-13)21(27)31/h1-7,10-11,16,30H,8-9,12H2,(H2,27,31)(H,28,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM191089 (US9181258, 77) Show SMILES NC(=O)c1ccc(cc1)-c1c(cc2C(=O)NCC(CCO)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H20F3N3O4/c24-23(25,26)33-17-3-1-2-15(10-17)18-11-19-22(32)28-12-16(8-9-30)29(19)20(18)13-4-6-14(7-5-13)21(27)31/h1-7,10-11,16,30H,8-9,12H2,(H2,27,31)(H,28,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
					More data for this Ligand-Target Pair