BDBM191129 US9181258, 130

SMILES: NCC[C@H]1CNC(=O)c2cc(c(-c3ccc(cc3)C3(N)CC3)n12)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=NEORABJLFZZFEQ-SFHVURJKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM191129 (US9181258, 130) Show SMILES NCC[C@H]1CNC(=O)c2cc(c(-c3ccc(cc3)C3(N)CC3)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C25H25F3N4O2/c26-25(27,28)34-19-3-1-2-16(12-19)20-13-21-23(33)31-14-18(8-11-29)32(21)22(20)15-4-6-17(7-5-15)24(30)9-10-24/h1-7,12-13,18H,8-11,14,29-30H2,(H,31,33)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM191129 (US9181258, 130) Show SMILES NCC[C@H]1CNC(=O)c2cc(c(-c3ccc(cc3)C3(N)CC3)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C25H25F3N4O2/c26-25(27,28)34-19-3-1-2-16(12-19)20-13-21-23(33)31-14-18(8-11-29)32(21)22(20)15-4-6-17(7-5-15)24(30)9-10-24/h1-7,12-13,18H,8-11,14,29-30H2,(H,31,33)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
					More data for this Ligand-Target Pair