BDBM191132 US9181258, 148

SMILES: Cc1cccc(c1)-c1c(cc2C(=O)NC[C@H](CCNC(N)=N)n12)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=YJVVLQUVYXOXOT-KRWDZBQOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM191132 (US9181258, 148) Show SMILES Cc1cccc(c1)-c1c(cc2C(=O)NC[C@H](CCNC(N)=N)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C24H24F3N5O2/c1-14-4-2-6-16(10-14)21-19(15-5-3-7-18(11-15)34-24(25,26)27)12-20-22(33)31-13-17(32(20)21)8-9-30-23(28)29/h2-7,10-12,17H,8-9,13H2,1H3,(H,31,33)(H4,28,29,30)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM191132 (US9181258, 148) Show SMILES Cc1cccc(c1)-c1c(cc2C(=O)NC[C@H](CCNC(N)=N)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C24H24F3N5O2/c1-14-4-2-6-16(10-14)21-19(15-5-3-7-18(11-15)34-24(25,26)27)12-20-22(33)31-13-17(32(20)21)8-9-30-23(28)29/h2-7,10-12,17H,8-9,13H2,1H3,(H,31,33)(H4,28,29,30)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
					More data for this Ligand-Target Pair