BDBM191785 US9187428, 13
SMILES: Nc1nc(SCc2ccnc(c2)C(=O)NC2CC2)c(C#N)c(-c2ccccc2)c1C#N
InChI Key: InChIKey=ZZDYGBAXSRKELQ-UHFFFAOYSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM191785 (US9187428, 13) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 0.0800 | n/a | n/a | 7.4 | 37 |
Bayer Intellectual Property GmbH US Patent | Assay Description The following test protocol is used for pharmacologically characterizing cells and for the robot-assisted substance screening:The stock cultures ar... | US Patent US9187428 (2015) BindingDB Entry DOI: 10.7270/Q29Z93Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2b (Homo sapiens (Human)) | BDBM191785 (US9187428, 13) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 46 | n/a | n/a | 7.4 | 37 |
Bayer Intellectual Property GmbH US Patent | Assay Description The following test protocol is used for pharmacologically characterizing cells and for the robot-assisted substance screening:The stock cultures ar... | US Patent US9187428 (2015) BindingDB Entry DOI: 10.7270/Q29Z93Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM191785 (US9187428, 13) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 108 | n/a | n/a | 7.4 | 37 |
Bayer Intellectual Property GmbH US Patent | Assay Description The following test protocol is used for pharmacologically characterizing cells and for the robot-assisted substance screening:The stock cultures ar... | US Patent US9187428 (2015) BindingDB Entry DOI: 10.7270/Q29Z93Q4 | |||||||||||
More data for this Ligand-Target Pair |