BDBM192008 Antimycin A::[(2R,3S,6S,7R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate
SMILES: CCCCCCC1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)[C@@H](NC(=O)c2cccc(NC=O)c2O)[C@@H](C)OC1=O
InChI Key: InChIKey=UIFFUZWRFRDZJC-RBVQMQRASA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome b (Candida albicans (Yeast)) | BDBM192008 (Antimycin A | [(2R,3S,6S,7R)-3-[(3-formamido-2-hyd...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Massachusetts Institute of Technology | Assay Description The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf... | Cell Chem Biol 23: 978-991 (2016) Article DOI: 10.1016/j.chembiol.2016.06.016 BindingDB Entry DOI: 10.7270/Q2SX6C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b (Homo sapiens (Human)) | BDBM192008 (Antimycin A | [(2R,3S,6S,7R)-3-[(3-formamido-2-hyd...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Massachusetts Institute of Technology | Assay Description The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf... | Cell Chem Biol 23: 978-991 (2016) Article DOI: 10.1016/j.chembiol.2016.06.016 BindingDB Entry DOI: 10.7270/Q2SX6C1B | |||||||||||
More data for this Ligand-Target Pair |