BDBM192106 Inz-97

SMILES: Fc1ccc(cc1-c1nn(Cc2cnccn2)c2ncccc12)C(F)(F)F

InChI Key: InChIKey=QQYOBFOPUWSQKV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome b (Homo sapiens (Human))	BDBM192106 (Inz-97) Show SMILES Fc1ccc(cc1-c1nn(Cc2cnccn2)c2ncccc12)C(F)(F)F Show InChI InChI=1S/C18H11F4N5/c19-15-4-3-11(18(20,21)22)8-14(15)16-13-2-1-5-25-17(13)27(26-16)10-12-9-23-6-7-24-12/h1-9H,10H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.44E+4	n/a	n/a	n/a	n/a	7.4	25
Massachusetts Institute of Technology					Assay Description The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...				Cell Chem Biol 23: 978-991 (2016) Article DOI: 10.1016/j.chembiol.2016.06.016 BindingDB Entry DOI: 10.7270/Q2SX6C1B
					More data for this Ligand-Target Pair
Cytochrome b (Candida albicans (Yeast))	BDBM192106 (Inz-97) Show SMILES Fc1ccc(cc1-c1nn(Cc2cnccn2)c2ncccc12)C(F)(F)F Show InChI InChI=1S/C18H11F4N5/c19-15-4-3-11(18(20,21)22)8-14(15)16-13-2-1-5-25-17(13)27(26-16)10-12-9-23-6-7-24-12/h1-9H,10H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	935	n/a	n/a	n/a	n/a	7.4	25
Massachusetts Institute of Technology					Assay Description The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...				Cell Chem Biol 23: 978-991 (2016) Article DOI: 10.1016/j.chembiol.2016.06.016 BindingDB Entry DOI: 10.7270/Q2SX6C1B
					More data for this Ligand-Target Pair