BDBM192151 US9187441, 7C
SMILES: CCOC(=O)c1c(C(N(CC(C)C)C(C)=O)C(=O)NCc2ccccc2)c2ccc(Cl)cc2n1C(=O)OC(C)(C)C
InChI Key: InChIKey=VQCRNHQPUUAGIY-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM192151 (US9187441, 7C) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.810 | -12.2 | n/a | n/a | n/a | n/a | n/a | n/a | 20 |
University of Pittsburgh—Of the Commonwealth System of Higher Education US Patent | Assay Description Fluorescent polarization experiments were performed as follows. Briefly, the fluorescence polarization experiments were read on an Ultra Evolution 38... | US Patent US9187441 (2015) BindingDB Entry DOI: 10.7270/Q2DR2T9N | |||||||||||
More data for this Ligand-Target Pair |