BDBM192204 US9187441, 6M
SMILES: CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(N(Cc1cc(F)c(F)c(F)c1)C=O)C(=O)NC(C)(C)C
InChI Key:
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM192204 (US9187441, 6M) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.400 | -12.6 | n/a | n/a | n/a | n/a | n/a | n/a | 20 |
University of Pittsburgh—Of the Commonwealth System of Higher Education US Patent | Assay Description Fluorescent polarization experiments were performed as follows. Briefly, the fluorescence polarization experiments were read on an Ultra Evolution 38... | US Patent US9187441 (2015) BindingDB Entry DOI: 10.7270/Q2DR2T9N | |||||||||||
More data for this Ligand-Target Pair |