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SMILES: CN1CCN(CC1)c1ccc(cn1)-c1cc2c(Cl)cccc2c(=O)[nH]1

InChI Key: InChIKey=LXGJXBNLJBEOLE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192900   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase tankyrase-1 [1068-1325]


(Homo sapiens (Human))		BDBM192900
PNG
(US9193689, IQ-002)
Show SMILES CN1CCN(CC1)c1ccc(cn1)-c1cc2c(Cl)cccc2c(=O)[nH]1
Show InChI InChI=1S/C19H19ClN4O/c1-23-7-9-24(10-8-23)18-6-5-13(12-21-18)17-11-15-14(19(25)22-17)3-2-4-16(15)20/h2-6,11-12H,7-10H2,1H3,(H,22,25)
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PC cid
PC sid
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Similars
US Patent
n/an/a 39n/an/an/an/an/an/a



INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE)

US Patent


Assay Description
Tankyrase activity was assayed using a 96-well format HT Universal Chemiluminescent PARP Assay Kit (Trevigen, Inc, cat. no. 4676-096-K) according to ...

US Patent US9193689 (2015)


BindingDB Entry DOI: 10.7270/Q29S1PTR
More data for this
Ligand-Target Pair