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SMILES: CN(C)Cc1ccc(cc1)-c1cc2ccccc2c(=O)[nH]1

InChI Key: InChIKey=HBXVMXCXZVJWOC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192903   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase tankyrase-1 [1068-1325]


(Homo sapiens (Human))		BDBM192903
PNG
(US9193689, REF-4)
Show SMILES CN(C)Cc1ccc(cc1)-c1cc2ccccc2c(=O)[nH]1
Show InChI InChI=1S/C18H18N2O/c1-20(2)12-13-7-9-14(10-8-13)17-11-15-5-3-4-6-16(15)18(21)19-17/h3-11H,12H2,1-2H3,(H,19,21)
PDB

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PC sid
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Similars
US Patent
n/an/a 18n/an/an/an/an/an/a



INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE)

US Patent


Assay Description
Tankyrase activity was assayed using a 96-well format HT Universal Chemiluminescent PARP Assay Kit (Trevigen, Inc, cat. no. 4676-096-K) according to ...

US Patent US9193689 (2015)


BindingDB Entry DOI: 10.7270/Q29S1PTR
More data for this
Ligand-Target Pair