null
SMILES: Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccc(cc2)S(=O)(=O)C(F)(F)F)cc1
InChI Key: InChIKey=YIRVMBRTDCZPQZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM19388 (2,4-diaminopyrimidine derivative, 8d | 6-[(benzylo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | 85 | n/a | n/a | 7.4 | 22 |
Abbott Laboratories | Assay Description Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ... | J Med Chem 49: 2568-78 (2006) Article DOI: 10.1021/jm0510934 BindingDB Entry DOI: 10.7270/Q27W69G1 | |||||||||||
More data for this Ligand-Target Pair |