BDBM194134 US9200001, 50

SMILES: Cc1nc(C)n(n1)-c1cc(CCc2ccc(C)cn2)nc(C)n1

InChI Key: InChIKey=ZEUCHGRYSQVYFK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM194134 (US9200001, 50) Show SMILES Cc1nc(C)n(n1)-c1cc(CCc2ccc(C)cn2)nc(C)n1 Show InChI InChI=1S/C17H20N6/c1-11-5-6-15(18-10-11)7-8-16-9-17(21-12(2)20-16)23-14(4)19-13(3)22-23/h5-6,9-10H,7-8H2,1-4H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...				US Patent US9200001 (2015) BindingDB Entry DOI: 10.7270/Q2BP01M3
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