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BDBM194134 US9200001, 50

SMILES: Cc1nc(C)n(n1)-c1cc(CCc2ccc(C)cn2)nc(C)n1

InChI Key: InChIKey=ZEUCHGRYSQVYFK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194134   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 10A (PDE10A2)


(Homo sapiens (Human))
BDBM194134
PNG
(US9200001, 50)
Show SMILES Cc1nc(C)n(n1)-c1cc(CCc2ccc(C)cn2)nc(C)n1
Show InChI InChI=1S/C17H20N6/c1-11-5-6-15(18-10-11)7-8-16-9-17(21-12(2)20-16)23-14(4)19-13(3)22-23/h5-6,9-10H,7-8H2,1-4H3
PDB

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
0.140n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...


US Patent US9200001 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01M3
More data for this
Ligand-Target Pair