BDBM194147 US9200001, 63
SMILES: CCOc1nc(cc(n1)-n1nc(C)nc1C)[C@@H]1C[C@H]1c1nc2ccccc2n1C
InChI Key: InChIKey=FMNRPWQOSKXAQP-HUUCEWRRSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human)) | BDBM194147 (US9200001, 63) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp... | US Patent US9200001 (2015) BindingDB Entry DOI: 10.7270/Q2BP01M3 | |||||||||||
More data for this Ligand-Target Pair |