BDBM194196 US9200001, 112

SMILES: Cc1nc(C)n(n1)-c1cc(nc(n1)C1CC1)[C@H]1C[C@@H]1c1nc2ccccc2n1C

InChI Key: InChIKey=FCTYHONQMCJEFG-HOTGVXAUSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM194196 (US9200001, 112) Show SMILES Cc1nc(C)n(n1)-c1cc(nc(n1)C1CC1)[C@H]1C[C@@H]1c1nc2ccccc2n1C |r| Show InChI InChI=1S/C22H23N7/c1-12-23-13(2)29(27-12)20-11-18(24-21(26-20)14-8-9-14)15-10-16(15)22-25-17-6-4-5-7-19(17)28(22)3/h4-7,11,14-16H,8-10H2,1-3H3/t15-,16-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...				US Patent US9200001 (2015) BindingDB Entry DOI: 10.7270/Q2BP01M3
					More data for this Ligand-Target Pair